In addition to Placement targeting, advertisers can bid on placement-targeted ads (formerly known as site-targeted ads) on a cost-per-click (CPC) basis. Previously, advertisers could only bid on these targeted ads on a cost-per-impression (CPM) basis. Just as with contextually targeted CPC ads, you’ll generate earnings for valid clicks on placement-targeted CPC ads.
Follow the link to learn more.
Inside AdSense: Say hello to placement targeting